Base-Pairing in DNA

• The hydrogen bonding between bases on different strands of DNA is known as base-pairing.

• Base-pairing only occurs between specific combinations of bases, hence it is often referred to as complementary base-pairing.

• The bases G and C always pair together, forming a G-C pair.

• The bases A and T always pair together, forming an A-T pair.

• These are known as the base-pairing rules.

Base-pairing in DNA only allows G-C pairs and A-T pairs.